Table 2.
Univariate and Multivariable Recurrence-Free Survival Analysis for Primary Patients in MSKCC data set.
| Univariate Analysis | Overall Variable P Value | Multivariable Analysis | ||||||
|---|---|---|---|---|---|---|---|---|
| Variable | Reference | Level | HR (95% CI) | Level Comparison P Value | HR (95% CI) | Level Comparison P Value | Overall Variable P Value | |
| Age at diagnosis (years) | <64 Years | > = 64 Year | 1.59 (0.69,3.65) | 0.2748 | 0.2748 | |||
| Gleason Score | 5–6 | 7 | 3.92 (0.89,17.25) | 0.0709 | <0.0001 | 2.37 (0.52, 10.78) | 0.2627 | <0.0001 |
| 5–6 | 8–10 | 31.19 (6.83,142.36) | <0.0001 | 19.5 (4, 95.09) | 0.0002 | |||
| Clinical Tumor Stage | T1C | T2,T2A,T2B,T2C | 0.69 (0.29,1.63) | 0.3994 | 0.0018 | |||
| T1C | T3,T3A,T3B,T3C | 6 (1.96,18.43) | 0.0017 | |||||
| Lymph node involvement | Normal_N0 | Abnormal_N1 | 8.67 (3.2,23.46) | <0.0001 | <0.0001 | 10.65 (3.18, 35.67) | 0.0001 | 0.0001 |
| Margin Status | Negative | Positive | 2.7 (1.26,5.79) | 0.0106 | 0.0106 | |||
| PSA at Diagnosis | <10 | > = 10 | 2.25 (0.98,5.17) | 0.0557 | 0.0557 | |||
| MKI67 | Low | High | 2.05 (0.95,4.43) | 0.0663 | 0.0663 | |||
| NEK2 | Low | High | 2.59 (1.16,5.78) | 0.0198 | 0.0198 | |||
| AURKA | Low | High | 0.81 (0.37,1.74) | 0.5810 | 0.5810 | |||
| BUB1 | Low | High | 3.02 (1.35,6.73) | 0.0069 | 0.0069 | 3.94 (1.58, 9.86) | 0.0034 | 0.0034 |
| CIT | Low | High | 1.62 (0.76,3.45) | 0.2117 | 0.2117 | |||
| HSPB8 | Low | High | 0.5 (0.23,1.07) | 0.0725 | 0.0725 | |||
| NCAPG | Low | High | 2.54 (1.16,5.56) | 0.0198 | 0.0198 | |||
| TRPM8 | Low | High | 1.52 (0.69,3.32) | 0.2963 | 0.2963 | |||
| NUF2 | Low | High | 1.59 (0.75,3.41) | 0.2294 | 0.2294 | |||
Backwards Selection at removal alpha = 0.05.