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. 2019 Jul 4;10(7):514. doi: 10.1038/s41419-019-1707-x

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 5 — a, b The effect of SNHG14 on EZH2 expression in indicated CRC cells was detected by qRT-PCR and western blot analysis. c Luciferase reporter assay was conducted to assess the influence of SNHG14 on EZH2 transcription. d RIP assay validated the common interaction of FUS with both SNHG14 and EZH2 mRNA. e The impact of SNHG14 on FUS-interacted EZH2 mRNA was estimated by preforming RIP assay. f qRT-PCR result of EZH2 level in indicated CRC cells. g The degradation rate of EZH2 mRNA in indicated CRC cells under the treatment of actinomycin D was tested by qRT-PCR. ^*P < 0.05, ^**P < 0.01