Table 4.
The results of conditional logistic regression, assessing the association between serious infection and clinical characteristics in systemic lupus erythematosus.
| Variables | COR | 95% CI | p | AOR | 95% CI | p | ||
|---|---|---|---|---|---|---|---|---|
| Age on diagnosis, years | 1.00 | 0.98 | 1.02 | 0.73 | 1.00 | 0.98 | 1.02 | 0.898 |
| Sex | ||||||||
| Male | 1.00 | 1.00 | ||||||
| Female | 0.81 | 0.4 | 1.62 | 0.548 | 0.9 | 0.38 | 2.14 | 0.793 |
| WBC | 1.00 | 1.00 | 1.00 | 0.604 | 1.00 | 1.00 | 1.00 | 0.234 |
| N/L ratio | 1.01 | 0.99 | 1.03 | 0.556 | 0.99 | 0.97 | 1.02 | 0.595 |
| Hemoglobin, /µL | 0.82 | 0.73 | 0.92 | 0.001 | 0.89 | 0.76 | 1.03 | 0.125 |
| Platelet, x 103/µL | 1.00 | 1.00 | 1.00 | 0.462 | 1.00 | 1.00 | 1.01 | 0.183 |
| ESR, mm/h | 1.00 | 1.00 | 1.01 | 0.363 | 1.00 | 0.99 | 1.01 | 0.78 |
| Complement 3, mg/dL | 0.99 | 0.99 | 1.00 | 0.043 | 1.00 | 0.99 | 1.01 | 0.63 |
| Complement 4, mg/dL | 0.99 | 0.97 | 1.01 | 0.538 | 1.01 | 0.98 | 1.05 | 0.544 |
| Anti-dsDNA Ab | 1.00 | 1.00 | 1.01 | 0.162 | 1.00 | 0.99 | 1.01 | 0.833 |
| Oral ulcer, n (%) | ||||||||
| No | 1.00 | 1.00 | ||||||
| Yes | 0.72 | 0.38 | 1.35 | 0.297 | 0.77 | 0.36 | 1.67 | 0.509 |
| Arthritis, n (%) | ||||||||
| No | 1.00 | 1.00 | ||||||
| Yes | 1.28 | 0.8 | 2.05 | 0.297 | 1.38 | 0.78 | 2.47 | 0.273 |
| Nephritis, n (%) | ||||||||
| No | 1.00 | 1.00 | ||||||
| Yes | 1.97 | 1.19 | 3.28 | 0.008 | 1.18 | 0.61 | 2.29 | 0.632 |
| Serositis, n (%) | ||||||||
| No | 1.00 | 1.00 | ||||||
| Yes | 2.61 | 1.47 | 4.61 | 0.001 | 2.76 | 1.33 | 5.74 | 0.007 |
| Hematologic involvement, n (%) | ||||||||
| No | 1.00 | 1.00 | ||||||
| Yes | 2.48 | 1.52 | 4.06 | <0.001 | 2.53 | 1.32 | 4.87 | 0.005 |
| Hydroxychloroquine, n (%) | ||||||||
| No | 1.00 | 1.00 | ||||||
| Yes | 0.34 | 0.16 | 0.69 | 0.003 | 0.42 | 0.17 | 1.03 | 0.06 |
| Mean GCs dose | ||||||||
| ≤7.5 mg/da | 1.00 | 1.00 | ||||||
| >7.5 mg/da | 2.34 | 1.38 | 3.95 | 0.001 | 2.65 | 1.31 | 5.34 | 0.007 |
| Immunosuppressive drugs, n (%) | ||||||||
| No | 1.00 | 1.00 | ||||||
| Yes | 1.39 | 0.87 | 2.23 | 0.171 | 0.67 | 0.35 | 1.27 | 0.22 |
COR: crude odds ratio, CI: confidence intervals, AOR: adjusted odds ratio, WBC: white blood cells, N/L ratio: Neutrophils/Lymphocyte ratio, ESR: erythrocyte sedimentation rate, dsDNA: double-strand deoxyribonucleic acid, Ab: antibody, GCs: glucocorticoids.
aPrednisolone-equivalent.