Table 3.
Performance of markers for identifying persons with prediabetes/diabetes, according to sex and age.
| Marker | Population | Cut-off | Sensitivity | Specificity | AUC (95% CI) | |
|---|---|---|---|---|---|---|
| VAI | Overall | 40 yrs | 1.28 | 0.706 | 0.570 | 0.690 (0.584–0.779) |
| 55 yrs | 1.46 | 0.711 | 0.590 | 0.701 (0.633–0.751) | ||
| 70 yrs | 1.88 | 0.484 | 0.730 | 0.633 (0.525–0.719) | ||
| Men | 40 yrs | 1.92 | 0.537 | 0.710 | 0.667 (0.572–0.770) | |
| 55 yrs | 1.10 | 0.868 | 0.340 | 0.639 (0.555–0.724) | ||
| 70 yrs | 1.60 | 0.507 | 0.660 | 0.611 (0.457–0.736) | ||
| Women | 40 yrs | 1.85 | 0.432 | 0.840 | 0.602 (0.404–0.844) | |
| 55 yrs | 1.23 | 0.821 | 0.510 | 0.714 (0.618–0.796) | ||
| 70 yrs | 1.47 | 0.728 | 0.510 | 0.655 (0.530–0.765) | ||
| LAP | Overall | 40 yrs | 33.99 | 0.698 | 0.640 | 0.728 (0.642–0.821) |
| 55 yrs | 41.78 | 0.720 | 0.640 | 0.743 (0.680–0.796) | ||
| 70 yrs | 50.22 | 0.550 | 0.650 | 0.611 (0.521–0.705) | ||
| Men | 40 yrs | 50.25 | 0.641 | 0.710 | 0.728 (0.620–0.787) | |
| 55 yrs | 63.63 | 0.545 | 0.730 | 0.669 (0.592–0.767) | ||
| 70 yrs | 51.80 | 0.537 | 0.650 | 0.574 (0.458–0.739) | ||
| Women | 40 yrs | 26.85 | 0.646 | 0.640 | 0.657 (0.492–0.849) | |
| 55 yrs | 42.98 | 0.650 | 0.740 | 0.746 (0.663–0.827) | ||
| 70 yrs | 42.26 | 0.658 | 0.570 | 0.632 (0.515–0.746) | ||
| TyG | Overall | 40 yrs | 8.65 | 0.650 | 0.760 | 0.776 (0.718–0.834) |
| 55 yrs | 8.68 | 0.691 | 0.670 | 0.745 (0.711–0.795) | ||
| 70 yrs | 8.58 | 0.715 | 0.590 | 0.712 (0.625–0.779) | ||
| Men | 40 yrs | 8.82 | 0.627 | 0.730 | 0.732 (0.647–0.800) | |
| 55 yrs | 8.80 | 0.666 | 0.630 | 0.689 (0.624–0.766) | ||
| 70 yrs | 8.72 | 0.630 | 0.660 | 0.685 (0.564–0.801) | ||
| Women | 40 yrs | 8.35 | 0.646 | 0.660 | 0.700 (0.580–0.832) | |
| 55 yrs | 8.53 | 0.782 | 0.650 | 0.786 (0.722–0.843) | ||
| 70 yrs | 8.48 | 0.782 | 0.500 | 0.684 (0.590–0.781) | ||
| HOMA-IR | Overall | 40 yrs | 2.39 | 0.590 | 0.780 | 0.761 (0.665–0.861) |
| 55 yrs | 2.31 | 0.686 | 0.770 | 0.810 (0.729–0.864) | ||
| 70 yrs | 2.63 | 0.553 | 0.830 | 0.733 (0.646–0.829) | ||
| Men | 40 yrs | 2.36 | 0.693 | 0.770 | 0.792 (0.713–0.882) | |
| 55 yrs | 2.64 | 0.651 | 0.780 | 0.761 (0.651–0.812) | ||
| 70 yrs | 2.37 | 0.726 | 0.770 | 0.819 (0.714–0.915) | ||
| Women | 40 yrs | 2.22 | 0.541 | 0.720 | 0.669 (0.593–0.907) | |
| 55 yrs | 2.26 | 0.833 | 0.800 | 0.892 (0.758–0.932) | ||
| 70 yrs | 2.50 | 0.588 | 0.810 | 0.743 (0.606–0.844) | ||
AUC (95% CI), area under the ROC curve (95% Confidence Interval). Cut-off value with corresponding sensitivity, specificity, and AUC estimated for 40, 55, and 70 years of age by induced method of non-parametric ROC regression (1000 bootstraps).