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. 2019 Jul 2;12(9):1213–1220. doi: 10.1016/j.tranon.2019.05.015

Figure 5.

Figure 5

Validation of the results in the G3 subgroup. (A) The box plots compare the relative levels of mtDNA79, mtDNA230 and the mtDNA integrity in the serum of healthy women (n = 60) and patients with G3 (n = 95). (B) The box plots compare the levels of mtDNA79, mtDNA230 and the mtDNA integrity in healthy women (n = 60) and in the patients with FIGO I-II (n = 25), III (n = 51) and IV (n = 19) confined in the G3 cohort. The scatter plots show the positive correlations of the relative amounts of (C) mtDNA79 and (D) mtDNA230 with the CA125 values of patients with G3 (n = 88). (E) The median values of mtDNA79 were used to group the EOC samples according to low (n = 43) and high (n = 43) mtDNA levels. Univariate Kaplan–Meier curves are related to low and high levels of mtDNA79 for patients' overall survival. *P < .05, **P < .01.