Table 6. Recommended antibiotics by pathogen.
Pathogen | First-line antibiotics | Second-line antibiotics |
---|---|---|
Campylobacter | Azithromycin | Ciprofloxacinb |
Non-typhoidal Salmonella | Usually not indicateda | NA |
Salmonella enterica Typhi or Paratyphi | Ceftriaxone or ciprofloxacin | Ampicillinb, TMP/SMXb, or azithromycin |
Shigella | Azithromycin, ciprofloxacinb, or ceftriaxone | TMP/SMXb or ampicillinb |
Vibrio cholerae | Doxycycline | Ciprofloxacin, azithromycin, or ceftriaxone |
Non-choleraic Vibrio | Noninvasive disease: usually not indicated | Noninvasive disease: usually not indicated |
Invasive disease: ceftriaxone + doxycycline | Invasive disease: TMP/SMX + aminoglycoside |
aCeftriaxone, ciprofloxacin, TMP/SMX, or amoxicillin may be used when there is a risk of invasive infections.
bHas a high risk of resistance in South Korea and may be used based on sensitivity test results. Caution is required when sensitivity is unknown (e.g., only positive PCR results).
NA, not available; TMP/SMX, trimethoprim-sulfamethoxazole.