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. 2019 Jun 26;51(2):217–243. doi: 10.3947/ic.2019.51.2.217

Table 6. Recommended antibiotics by pathogen.

Pathogen First-line antibiotics Second-line antibiotics
Campylobacter Azithromycin Ciprofloxacinb
Non-typhoidal Salmonella Usually not indicateda NA
Salmonella enterica Typhi or Paratyphi Ceftriaxone or ciprofloxacin Ampicillinb, TMP/SMXb, or azithromycin
Shigella Azithromycin, ciprofloxacinb, or ceftriaxone TMP/SMXb or ampicillinb
Vibrio cholerae Doxycycline Ciprofloxacin, azithromycin, or ceftriaxone
Non-choleraic Vibrio Noninvasive disease: usually not indicated Noninvasive disease: usually not indicated
Invasive disease: ceftriaxone + doxycycline Invasive disease: TMP/SMX + aminoglycoside

aCeftriaxone, ciprofloxacin, TMP/SMX, or amoxicillin may be used when there is a risk of invasive infections.

bHas a high risk of resistance in South Korea and may be used based on sensitivity test results. Caution is required when sensitivity is unknown (e.g., only positive PCR results).

NA, not available; TMP/SMX, trimethoprim-sulfamethoxazole.