Figure 5. Both DOX and DTX activate NF-κB pathway and promote IFN production in the PDTX model.

(A) Protein levels of p-65 are analyzed in lung tissues in PDTX mice treated with DOX and DTX. (B) Serum levels of IFN-γ were evaluated in PDTX mice treated with DOX and DTX by ELISA analysis. Data were shown as mean ± SD, *P<0.05, **P<0.01.