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. 2019 Jun 28;110(7):2166–2179. doi: 10.1111/cas.14074

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© 2019 The Authors. Cancer Science published by John Wiley & Sons Australia, Ltd on behalf of Japanese Cancer Association.

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

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Population level analysis. A (Upper) Immunohistochemical results of adjacent tissue (left) and CCA tissue (right). (Lower) Expression of RNA component of mitochondrial RNA processing endoribonuclease (RMRP) in adjacent tissues and cholangiocarcinoma (CCA) tissues by qRT‐PCR. B, Unpaired t test analysis of RMRP expression in CCA tissues of stage I/II patients and stage III patients. C, Kaplan‐Meier overall survival curves according to the expression of RMRP. D, Expression of RMRP was negatively correlated with that of microRNA (miR)‐217 in CCA tissues. Representative data are based on three independent experiments. Bars, ±SD