Figure 1.

Schematic Representation of Somatic Mutations within a Phased Sample

(A) A mosaic mutation occurs on haplotype H2.

(B) Therefore, in linked-read sequencing, where short reads can be phased when linked reads overlap phased heterozygous variants, mosaic mutations manifest on reads from only one haplotype, here H2. Adapted from Figure 3 of Dou et al., 2018.