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. 2019 Jun 20;15:100499. doi: 10.1016/j.ajoc.2019.100499

Fig. 1.

Fig. 1

Time series slit lamp biomicroscopy images documenting the clinical course. (A) 7 weeks following the first PACK-CXL, Acanthamoeba infection is suspected and a central thinning is observed. (B, C) Lesion area with surrounding ring-shaped opacity observed after 3 weeks of anti-amoebic therapy. The lesion and surrounding opacity is stained with fluorescein. (D, E) Lesion area 2 weeks later, with distinct ring-shaped opacity evident and large central de-epithelized area. (F) Three days following the second PACK-CXL procedure. (G) Two weeks after the second PACK-CXL procedure. (H) Nine weeks after the second PACK-CXL procedure, only a small inferior de-epithelized area remains. (I) At 11 weeks, the clinical picture remained relatively unchanged. (J) At four months, healing has continued and the lesion size has further diminished. (K) Five months after the second PACK-CXL treatment, only intermittent punctate staining of the epithelium is found and the eye is stable and pain-free.