Table 2.
Calculated parameters of CH2879 cell survival after irradiation with X-rays, protons, and C-ions with and without PARPi (from Fig. 4).
| D10a | D37b | SF2c | ER (D10)d | ER (D37)e | |
|---|---|---|---|---|---|
| X-rays | 5.9 | 3.8 | 0.75 | / | / |
| X-rays + PARPi | 4.3 | 3 | 0.7 | 1.37 | 1.27 |
| Protons | 5.1 | 2.7 | 0.5 | / | / |
| Protons + PARPi | 2.9 | 1.4 | 0.2 | 1.76 | 1.93 |
| C-ions | 2 | 0.9 | 0.1 | / | / |
| C-ions + PARPi | 1.4 | 0.6 | 0.03 | 1.43 | 1.5 |
a
the D10 dose gives a surviving fraction of 0.1.
b
the D37 dose gives a surviving fraction of 0.37.
c
the SF2 fraction is observed at 2 Gy irradiation.
d
ER (D10) values are calculated as: D10 (with PARPi) / D10 (without PARPi) for each irradiation quality.
e
ER (D37) values are calculated as: D37 (with PARPi) / D37 (without PARPi) for each irradiation quality.