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. 2019 Jun 28;10:1337. doi: 10.3389/fmicb.2019.01337

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Copyright © 2019 Cordeiro, Evangelista, Serpa, Andrade, Mendes, Oliveira, Alencar, Pereira, Lima-Neto, Brilhante, Sidrim, Maia and Rocha.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effect of CEF and AMOX on C. albicans ATCC 10231 biofilm regarding to biomass (A), metabolic activity (B), viable cell counts (C), chitin content normalized per biomass (D), and proteolytic activity (E). Black bars: drug-free control; gray bars: treatment with CEF; white bars: treatment with AMOX. Panels (A–C) show analyses of 6-, 24-, and 48-h-grown biofilms. Panels (D,E) show analyses of 48-h-grown biofilms. Experiments were conducted in triplicate. ^∗Statistically significant differences when compared to the respective drug-free control (P < 0.05), according to ANOVA and Tukey test.