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. 2019 Jun 24;4(3):332–344. doi: 10.1016/j.jacbts.2019.01.008

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© 2019 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Atrial Hypertrophy

Representative histological images of (A) hematoxylin and eosin–stained LA tissue preparations in I/R-Sham rats, I/R-rats given placebo, and I/R-rats treated with ramipril or SAR. (B) Ratio of LA weight per 100 g body weight of I/R-Sham (n = 9), I/R-Placebo (n = 12), I/R-Ramipril (n = 12), and I/R-SAR (n = 13) rats. (C) Quantification of LA myocyte diameter and (D) brain natriuretic peptide (BNP) mRNA level in the left atrium in I/R-Sham (n = 9), I/R-rats given placebo (n = 11-12) and I/R-rats treated with ramipril (n = 11-12) or SAR (n = 11-14). Values are mean ± SEM. Abbreviations as in Figures 1, 2, and 4.