Figure 2.

RRs and 95% CI of GDM according to prepregnancy supplemental (A) and food folate (B) intake by MTHFR C677T genotypes among white women. The CC/CT and TT groups included 1,136 and 177 pregnancies, respectively. Models adjusted for age (months), nulliparity (yes, no), family history of diabetes (yes, no), physical activity (MET h/week), prepregnancy BMI (<25.0, 25.0‒29.9, and >30.0 kg/m²), current smoking (yes, no), alcohol use (yes, no), and dietary intakes of total energy (kcal/day), glycemic load (unit), saturated fat (% energy), total fiber (g/day), and heme iron (mg/day). Three categories of supplemental folate intake were used instead of four to avoid small numbers in some categories. Q, quartile.