Table 2.
Multivariable adjusted logistic regression for major amputations (n = 19,939,716 hospital admissions)
| Variable | OR | CI 95% | P value |
|---|---|---|---|
| Diabetes | 2.39 | 2.34, 2.44 | <0.001* |
| CKD | 1.47 | 1.43, 1.51 | <0.001* |
| Hyperlipidemia | 0.71 | 0.7, 0.73 | <0.001* |
| Hypertension | 1.01 | 0.98, 1.03 | 0.59 |
| PAD | 78.41 | 76.63, 80.23 | <0.001* |
| Smoker | 1.07 | 1.04, 1.11 | <0.001* |
| Race/ethnicity Hispanic† | 1.51 | 1.48, 1.55 | <0.001* |
| Race/ethnicity non-Hispanic black† | 1.97 | 1.92, 2.02 | <0.001* |
| Male sex | 1.69 | 1.66, 1.72 | <0.001* |
| Insurance (private, Medicare, or Medicaid) | 0.77 | 0.75, 0.8 | <0.001* |
| CAD | 0.79 | 0.77, 0.81 | <0.001* |
| Stroke/TIA | 0.37 | 0.34, 0.41 | <0.001* |
| Congestive heart failure | 1.09 | 1.04, 1.13 | <0.001* |
| Chronic obstructive pulmonary disease | 1.10 | 1.07, 1.13 | <0.001* |
| Year | 0.99 | 0.98, 0.99 | <0.001* |
| Age >65 years (senior) | 1.18 | 1.16, 1.21 | <0.001* |
| Revascularization (surgical and/or endovascular) | 0.52 | 0.5, 0.54 | <0.001* |
Significant P values appear in boldface type.
*P < 0.05.
†Non-Hispanic white is the reference group.