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. 2019 Apr 22;68(7):1415–1426. doi: 10.2337/db18-1307

Figure 6.

Figure 6

Fecal microbiota transfer (FMT) from WT and Fpr1-KO HFD donor mice to GF recipient mice leads to glucose intolerance. A: OG-GTT of GF mice fed a NCD or placed on an HFD and gavaged with fecal preparations from WT or Fpr1-KO mice fed an HFD (n = 3–4 mice/group; 8 weeks on an HFD). B: Basal insulin levels taken immediately prior to OG-GTTs. C: Active GLP-1 levels. D: Body weight at the time of OG-GTTs. E: Weight of eWAT. F: Weight of liver. *P < 0.05, **P < 0.001 by two-way ANOVA and Bonferroni post-test (A) or one-way ANOVA and Bonferroni post-test, comparing the indicated groups. In A, significance is indicated for GF vs. HFD + WT FMT animals at each respective time point.