Skip to main content
. 2019 Mar 20;68(6):1210–1220. doi: 10.2337/db18-1167

Figure 5.

Figure 5

Celastrol increases sympathetic traffic to kidney and iBAT. A: Representative images showing iBAT SNA recording at baseline and at the fifth hour of IV vehicle or celastrol (0.5 mg/kg). B: Five-hour time course of celastrol-induced changes of iBAT SNA from baseline activity. C: Representative images showing renal SNA (RSNA) recording at baseline and at the fifth hour of IV vehicle or celastrol (0.5 mg/kg). D: Five-hour time course of celastrol-induced changes of RSNA from baseline activity. E and F: Change in mean arterial pressure (ΔMAP) and heart rate (ΔHR) from baseline during 5-h SNA recording (N = 3–6/group). Data are presented as mean ± SEM. *P < 0.05, ***P < 0.001 by two-way ANOVA compared with vehicle group.