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. 2019 Jun 6;42(2):561–570. doi: 10.3892/or.2019.7187

Figure 1.

Figure 1.

BGC823 and MGC803 cells are relatively insensitive to IR. (A) Six gastric cancer cell lines (SGC7901, HGC-27, MKN45, MKN74, BGC823 and MGC803) were exposed to increasing doses of IR (0, 2, 4, 6 and 8 Gy). (B) Protein expression levels of γH2AX and cleaved-caspase3 were decreased, and PARP1 protein expression was increased, in BGC823 and MGC803 cells following IR (4 Gy). (C) Quantification of protein expression levels. **P<0.01 and ***P<0.0001 vs. SGC7901. IR, ionizing radiation; PARP1, poly [ADP-ribose] polymerase 1; γH2AX, γ H2A histone family member X.