Table 3.
Incidence of acute toxicity, n (%)
| Adverse effects | Arm A (n=51) | Arm B (n=50) | P value |
|---|---|---|---|
| Leukocytes | |||
| Grade 0-2 | 19 (37.2%) | 26 (52.0%) | |
| Grade 3-4 | 32 (62.8%) | 24 (48.0%) | 0.098 |
| Leukopenia | |||
| Grade 0-2 | 18 (35.3%) | 33 (66.0%) | |
| Grade 3-4 | 33 (64.7%) | 17 (34.0%) | 0.002 |
| Anemia | |||
| Grade 0-2 | 45 (90.0%) | 35 (62.0%) | |
| Grade 3-4 | 6 (10.0%) | 15 (30.0%) | 0.024 |
| Thrombocytopenia | |||
| Grade 0-2 | 44 (86.2%) | 30 (60.0%) | |
| Grade 3-4 | 7 (13.8%) | 20 (40.0%) | 0.003 |
| Pneumonitis | |||
| Grade 0-2 | 47 (92.2%) | 44 (88.0%) | |
| Grade 3 | 4 (7.8%) | 6 (12.0%) | 0.484 |
| Esophagitis | |||
| Grade 0-1 | 47 (92.2%) | 46 (92.0%) | |
| Grade 2 | 4 (7.8%) | 4 (8.0%) | 0.625 |
| Gastrointestinal | |||
| Grade 0-2 | 45 (88.2%) | 47 (94.0%) | |
| Grade 3 | 6 (11.8%) | 3 (6.0%) | 0.309 |