Table 3.

Multivariate Cox proportional-hazards analysis in total patients

Variable	OS
	HR	95% CI	P value
Tumor size (< 5 cm vs. ≥ 5 cm)	2.045	1.204-3.474	0.003
Vascular invasion (Negative vs. Positive)	1.796	1.115-2.894	0.006
Child-Pugh Classification Grade (A vs. B and C)	1.620	1.001-2.620	< 0.001
Reaction (Negative vs. Positive)	0.491	0.268-0.899	0.006