Table 2.
All AML patients (n = 17 120) | APL (n = 1193) | Non-APL (n = 15 927) | ||||
---|---|---|---|---|---|---|
Characteristic | Incidence rate (95% CI) | Incidence rate ratio (95% CI) | Incidence rate (95% CI) | Incidence rate ratio (95% CI) | Incidence rate (95% CI) | Incidence rate ratio (95% CI) |
Gendera | ||||||
Male | 5.3 (5.2–5.4) | 1.0 (Ref) | 0.3 (0.3–0.4) | 1.0 (Ref) | 5.0 (4.9–5.1) | Ref |
Female | 3.5 (3.5–3.6) | 0.67 (0.65–0.69) | 0.3 (0.3–0.3) | *0.85 (0.75–0.95) | 3.3 (3.2–3.3) | *0.65 (0.63–0.67) |
Racea | ||||||
White | 4.5 (4.4–4.6) | 1.0 (Ref) | 0.3 (0.3–0.3) | 1.0 (Ref) | 4.2 (4.1–4.3) | Ref |
Black | 3.0 (2.9–3.1) | 0.66 (0.63–0.70) | 0.2 (0.2–0.3) | *0.78 (0.65–0.92) | 2.8 (2.6–2.9) | *0.66 (0.62–0.69) |
Otherb | 3.5 (3.2–3.7) | 0.77 (0.71–0.82) | 0.3 (0.2–0.3) | 0.87 (0.68–1.10) | 3.2 (3.0–3.4) | *0.76 (0.71–0.82) |
Ethnicitya | ||||||
Non-Hispanic | 4.3 (4.3–4.4) | 1.0 (Ref) | 0.3 (0.3–0.3) | 1.0 (Ref) | 4.0 (4.0–4.1) | Ref |
Hispanic | 3.4 (3.2–3.6) | 0.79 (0.75–0.83) | 0.4 (0.3–0.4) | *1.22 (1.02–1.43) | 3.1 (2.9–3.3) | *0.76 (0.71–0.80) |
Birthplacec,d | ||||||
USA-born | 4.2 (3.9–4.6) | 1.0 (Ref) | 0.2 (0.2–0.3) | 1.0 (Ref) | 4.0 (3.6–4.3) | Ref |
Foreign-born | 3.5 (3.3–3.7) | 0.84 | 0.3 (0.2–0.4) | 1.18f | 3.2 (3.0–3.5) | 0.82f |
Unknown | — | — | — | |||
Birthplacec,e | ||||||
USA-born | 4.7 (4.4–5.1) | 1.0 (Ref) | 0.3 (0.2–0.4) | 1.0 (Ref) | 4.4 (4.1–4.8) | Ref |
Foreign-born | 4.0 (3.6–4.2) | 0.85 | 0.4 (0.3–0.5) | 1.20f | 3.6 (3.4–3.9) | 0.83f |
aAge-adjusted incidence rates per 100 000 using 19 age groups from the 2000 USA standard population.
bAmerican Indian/Alaskan Native, Asian/Pacific Islander.
cAge-adjusted annual average incidence rates, based on 2000 USA Census estimates for age distribution of USA and foreign-born subjects.
dData for ‘Unknown’ birth place excluded, denominators are either USA-born or foreign-born subjects.
eSensitivity analysis incorporating ‘Unknown’ birth place cases proportionately distributed within ‘USA-born’ and ‘Foreign-born’ categories.
fStandard errors for rate ratios not estimable due to aggregate denominator data.
*P ≤ 0.05.