Table 5.

Cox proportional analysis for 5-year mortality by initial vascular access for hemodialysis

Variable	All cohort		< 65 Years		65–74 Years		≥ 75 Years
	HR (95% CI)	p valuea	HR (95% CI)	p valuea	HR (95% CI)	p valuea	HR (95% CI)	p valuea
Percutaneous catheter
Unadjusted	1.70 (1.38–2.09)	< 0.001	1.18 (0.89–1.56)	0.226	2.43 (1.82–3.23)	< 0.001	2.78 (1.92–4.03)	< 0.001
Adjusted for age	1.82 (1.47–2.24)	< 0.001	1.26 (0.95–1.66)	0.096	2.41 (1.81–3.21)	< 0.001	2.72 (1.88–3.95)	< 0.001
Model 1 + sex	1.85 (1.50–2.29)	< 0.001	1.27 (0.96–1.68)	0.087	2.43 (1.82–3.23)	< 0.001	2.74 (1.89–3.97)	< 0.001
Model 2 + diabetes, heart failure	1.83 (1.49–2.26)	< 0.001	1.27 (0.96–1.67)	0.091	2.44 (1.83–3.25)	< 0.001	2.74 (1.89–3.98)	< 0.001
Model 3 + cardioprotective medicationb	1.84 (1.51–2.31)	< 0.001	1.25 (0.94–1.66)	0.111	2.44 (1.83–3.25)	< 0.001	2.77 (1.90–4.03)	< 0.001
Model 4 + albumin < 3.5 g/dL	1.79 (1.45–2.22)	< 0.001	1.10 (0.82–1.46)	0.519	2.29 (1.72–3.06)	< 0.001	2.51 (1.72–3.69)	< 0.001
Model 5 + hemoglobin < 10.0 g/dL	1.78 (1.44–2.21)	< 0.001	1.10 (0.83–1.47)	0.489	2.33 (1.74–3.12)	< 0.001	2.49 (1.70–3.66)	< 0.001
Model 6 + vascular conversion	1.64 (1.31–2.05)	< 0.001	1.28 (0.89–1.82)	0.752	1.97 (1.35–2.74)	< 0.001	1.89 (1.10–3.26)	0.021
Tunneled cuffed catheter
Unadjusted	1.65 (1.38–1.97)	< 0.001	1.28 (0.92–1.78)	0.134	2.27 (1.64–3.13)	< 0.001	1.92 (1.23–2.98)	< 0.001
Adjusted for age	1.72 (1.44–2.05)	< 0.001	0.90 (0.70–1.16)	0.424	2.27 (1.64–3.13)	< 0.001	1.89 (1.21–2.94)	< 0.001
Model 1 + sex	1.73 (1.45–2.07)	< 0.001	1.46 (1.05–2.04)	0.024	2.32 (1.68–3.20)	< 0.001	1.91 (1.22–2.98)	< 0.001
Model 2 + diabetes, heart failure	1.77 (1.48–2.11)	< 0.001	1.48 (1.06–2.07)	0.019	2.30 (1.66–3.17)	< 0.001	1.91 (1.23–2.98)	< 0.001
Model 3 + cardioprotective medicationb	1.78 (1.48–2.13)	< 0.001	1.46 (1.05–2.04)	0.025	2.25 (1.62–3.11)	< 0.001	1.95 (1.25–3.05)	0.003
Model 4 + albumin < 3.5 g/dL	1.64 (1.39–1.97)	< 0.001	1.10 (0.82–1.46)	0.080	2.25 (1.62–3.11)	< 0.001	1.89 (1.21–2.96)	0.005
Model 5 + hemoglobin < 10.0 g/dL	1.64 (1.36–1.98)	< 0.001	1.31 (0.93–1.85)	0.115	2.24 (1.61–3.11)	< 0.001	1.96 (1.25–3.07)	0.003
Model 6 + vascular conversion	1.41 (1.13–1.75)	0.002	1.04 (0.74–1.45)	0.802	1.93 (1.35–2.74)	< 0.001	1.34 (1.05–2.26)	0.038

HR, hazard ratio; CI, confidence interval.

^ap value for interaction between vascular access and age group is < 0.001.

^bOne of following: β-blocker, calcium channel blocker, angiotensin converting enzyme inhibitor, angiotensin receptor antagonist medication.