Table 1.
| Gene symbol | Protein name | Location |
|---|---|---|
| Signaling − Cell surface receptors | ||
| ACVRL1 | Activin A receptor 2-like 1 | Cell surface |
| FGFR2 | FGF receptor 2 | Cell surface |
| NPR3 | Atrial natriuretic peptide receptor 3 | Cell surface |
| SDC2 | Syndecan 2 | Cell surface |
| TGFBR3 | TGFβ receptor III | Cell surface |
| TRPV4 | Transient receptor potential cation channel V4 | Cell surface |
| UNC5B | Netrin receptor UNC5B | Cell surface |
| EFNA1 | Ephrin A1 | Cell surface |
| Signaling − Cytoskeleton related | ||
|---|---|---|
| ANXA1 | Annexin A1 | Cell surface |
| ANXA2 | Annexin A2 | Cell surface |
| CAPN2 | Calpain 2 | Cell surface |
| CAPNS1 | Calpain small subunit 1 | Cell surface |
| GJA1 | Connexin 43 | Cell surface |
| ACTA2 | Smooth muscle actin | Intracellular |
| NGEF | Neuronal guanine nucleotide exchange factor | Intracellular |
| Signaling − Transcription regulators | ||
|---|---|---|
| HIF1A | Hypoxia-inducible factor 1α | Intracellular |
| RARB | Retinoic acid receptor β | Intracellular |
| RXRB | Retinoid X receptor β | Intracellular |
| VDR | Vitamin D receptor | Intracellular |
| Signaling − Secreted | ||
|---|---|---|
| ANGPTL7 | Angiopoietin-related protein 7 | Extracellular |
| IGF1 | Insulin-like growth factor 1 | Extracellular |
| IGF2 | Insulin-like growth factor 2 | Extracellular |
| IL18 | Interleukin 18 | Extracellular |
| PENK | Proenkephalin A | Extracellular |
| TGFB1 | Transforming growth factor β1 | Extracellular |
| TGFB2 | Transforming growth factor β2 | Extracellular |
| TGFBI | TGFβ-induced protein | Extracellular |
| Signaling − Matricellular | ||
|---|---|---|
| CTGF | Connective tissue growth factor | Extracellular |
| CYR61 | Protein CYR61 | Extracellular |
| FBLN1 | Fibulin 1 | Extracellular |
| NOV | Nephroblastoma overexpressed gene | Extracellular |
| SPARC | Secreted protein acidic and rich in cysteine | Extracellular |
| SPP1 | Osteopontin | Extracellular |
| THBS1 | Thrombospondin 1 | Extracellular |
| THBS2 | Thrombospondin 2 | Extracellular |
| TNC | Tenascin C | Extracellular |
| WISP1 | WNT1 inducible signaling pathway protein 1 | Extracellular |
| MPs / TIMPs | ||
|---|---|---|
| ADAMTS5 | ADAM metallopeptidase with thrombospondin motif, 5 | Extracellular |
| MMP2 | Matrix metallopeptidase 2 | Extracellular |
| MMP14 | Matrix metallopeptidase 14 | Cell surface |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | Extracellular |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | Extracellular |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | Extracellular |
| Extracellular matrix − Collagens | ||
|---|---|---|
| COL1A1 | Collagen type I, α1 | Extracellular |
| COL12A1 | Collagen type XII, α1 | Extracellular |
| COL14A1 | Collagen type XIV, α1 | Extracellular |
| Extracellular matrix − Proteoglycans | ||
|---|---|---|
| ACAN | Aggrecan | Extracellular |
| DCN | Decorin | Extracellular |
| FMOD | Fibromodulin | Extracellular |
| KERA | Keratocan | Extracellular |
| NYX | Nyctalopin | Extracellular |
| OGN | Mimecan | Extracellular |
| PRELP | Prolargin | Extracellular |
| Extracellular matrix-Other | ||
|---|---|---|
| HS6ST1 | Heparan-sulfate 6-O-sulfotransferase 1 | Cell surface |
| SERPINH1 | Serpin H1 | Intracellular |