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. 2019 Jan 11;29(8):4276–4285. doi: 10.1007/s00330-018-5942-9

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© The Author(s) 2019

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 3 — a T1-weighted MRI with a contrast-enhancing lesion (cyan arrow) and the arteria carotis interna (orange arrow). b ROI_TBR delineation of a tumour in the PET image after AC using the model-based approach. In this case, the ROI_TBR additionally includes parts of the arteria carotis interna. c TACs extracted from ROI_TBR (red) and from two manually drawn ROIs in the tumour (ROI_Tumour, cyan) and the arteria carotis interna (ROI_Vessel, orange). The TAC extracted from ROI_TBR is a mixture of the TAC extracted from ROI_Tumour and ROI_Vessel