Table 4.
ROC analyses of different models in predicting 2-year progression-free survival
| Models | AUC | SEN (%) | SPE (%) | PPV (%) | NPV (%) |
|---|---|---|---|---|---|
| CE-T1WI-based uniformity | 0.710 (0.530, 0.889) | 76.2 | 66.7 | 86.5 | 50.0 |
| (60.2, 87.2) | (38.7, 98.0) | (70.4, 94.9) | (27.9, 72.1) | ||
| Overall stage | 0.636 (0.519, 0.752) | 40.5 | 86.7 | 89.5 | 34.2 |
| (26.0, 56.7) | (58.4, 97.7) | (65.5, 98.2) | (20.1, 51.4) | ||
| Tumour volume | 0.659 (0.472, 0.846) | 78.6 | 60.0 | 84.6 | 50.0 |
| (62.8, 89.2) | (32.9, 82.5) | (68.8, 93.6) | (26.8, 73.2) | ||
| CE-T1WI-based uniformity + overall stage | 0.540 (0.365, 0.715) | 40.5 | 86.7 | 89.5 | 34.2 |
| (26.0, 56.7) | (58.4, 97.7) | (65.5, 98.2) | (20.1, 51.4) | ||
| CE-T1WI-based uniformity + tumour volume | 0.784 (0.625, 0.943) | 95.2 | 60.0 | 87.0 | 81.8 |
| (82.6, 99.2) | (32.9, 82.5) | (73.1, 94.6) | (47.8, 96.8) | ||
| CE-T1WI-based uniformity + overall stage + tumour volume | 0.825 (0.696, 0.955) | 85.7 | 73.3 | 90.0 | 64.7 |
| (70.8, 94.1) | (44.8, 91.1) | (75.4, 96.7) | (38.6, 84.7) |
CE-T1WI contrast-enhanced T1-weighted image, AUC area under the curve, SEN sensitivity, SPE specificity, PPV positive predictive value, NPV negative predictive value
Data in parentheses are 95% confidence intervals (CIs)