Table 3.
Sensitivity analysis for the association of serum vitamin B12 concentrations with obesity in 8,903 US adults with normal vitamin B12 concentrations.
| Serum vitamin B12 concentrations, pgl/ml | |||||
|---|---|---|---|---|---|
| Quartile 1 (200.0–393.0) |
Quartile 2 (394.0–526.0) |
Quartile 3 (527.0–723.0) |
Quartile 4 (≥724.0) |
P for trend | |
| No. of participants | 2,224 | 2,230 | 2,222 | 2,227 | |
| Model 1b | 1 (ref) | 0.90 (0.77, 1.06)a | 0.82 (0.72, 0.93) | 0.71 (0.60, 0.84) | 0.001 |
| Model 2c | 1 (ref) | 0.91 (0.77, 1.08) | 0.80 (0.69, 0.94) | 0.67 (0.57, 0.79) | <0.001 |
| Model 3d | 1 (ref) | 0.92 (0.77, 1.10) | 0.84 (0.73, 0.98) | 0.71 (0.60, 0.84) | <0.001 |
a
OR; 95% CI in parentheses (all such values).
b
Model 1: adjusted for age and gender.
c
Model 2: Model 1 plus race/ethnicity, education, family income, cigarette smoking, physical activity, alcohol intake, dietary vitamin B12 intake, and total energy intake, as categorized in Table 1.
d
Model 3: Model 2 plus use of metformin, histamine-2 blockers or proton pump inhibitors, dietary supplement use and fasting time.