Table 4.
Sensitivity analysis for the association of serum vitamin B12 concentrations with obesity in 4,567 US adults fasting more than 8 h.
Serum vitamin B12 concentrations, pgl/ml | |||||
---|---|---|---|---|---|
Quartile 1 (<380.0) |
Quartile 2 (380.0–512.0) |
Quartile 3 (513.0–700.0) |
Quartile 4 (≥701.0) |
P for trend | |
No. of participants | 1,135 | 1,150 | 1,141 | 1,141 | |
Model 1b | 1 (ref) | 0.91 (0.74, 1.13)a | 0.80 (0.67, 0.96) | 0.68 (0.54, 0.86) | <0.001 |
Model 2c | 1 (ref) | 0.87 (0.71, 1.08) | 0.79 (0.66, 0.95) | 0.64 (0.51, 0.80) | <0.001 |
Model 3d | 1 (ref) | 0.89 (0.72, 1.11) | 0.81 (0.67, 0.98) | 0.65 (0.51, 0.83) | <0.001 |
OR; 95% CI in parentheses (all such values).
Model 1: adjusted for age and gender.
Model 2: Model 1 plus race/ethnicity, education, family income, cigarette smoking, physical activity, alcohol intake, dietary vitamin B12 intake, and total energy intake, as categorized in Table 1.
Model 3: Model 2 plus use of metformin, histamine-2 blockers or proton pump inhibitors, dietary supplement use and fasting time.