Table 7.
Table with genes (described in this review) which are differently expressed among neuron subpopulations.
Gene | Gene acronym | Motor neurons | ||||||
---|---|---|---|---|---|---|---|---|
Cortical | Oculomotor | Onuf’s | Hypoglossal | Slow spinal cord | Fast spinal cord | References | ||
Vulnerable | Resistant | Resistant | Vulnerable | Resistant | Vulnerable | |||
Insulin-like growth factor I receptor | IGF-IR | + | – (cervical spinal MNs) | Allodi et al., 2016 | ||||
Insulin-like growth factor II | IGF-II | + | – | Hedlund et al., 2010; Allodi et al., 2016 | ||||
Glial cell line-derived neurotrophic factor receptor subunit | GFRα1 | Shneider et al., 2009 | ||||||
Semaphorin A3 | SemaA3 | + | + (FF) | De Winter et al., 2006 | ||||
Na+/K+ATPase-alpha3 | – | + | Ruegsegger et al., 2016 | |||||
AMPA receptor GluR2 subunits | GluR2 | + | Brockington et al., 2013 | |||||
calbindin-D28K | CaBP | – | + | + | Alexianu et al., 1994 | |||
Parvalbumin | – | + | Alexianu et al., 1994 | |||||
Calreticulin | CRT | – | Bernard-Marissal et al., 2012 | |||||
matrix metalloproteinase-9 | MMP-9 | – | – | + | Kaplan et al., 2014 | |||
Binding immunoglobulin protein co-chaperone | SIL-1 | + | – (FF) | Filézac de L’Etang et al., 2015 | ||||
Dynein | – | + | + (spinal MNs) | Comley et al., 2015 | ||||
(+), upregulation; (–), downregulation; gray, unknown.