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. 2019 Jun 27;6:145. doi: 10.3389/fmed.2019.00145

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Copyright © 2019 Moscowitz, Asif, Lindenmaier, Calzadilla, Zhang and Mirsaeidi.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Downstream effects of Melanocortin-1 receptor stimulation in melanocytes: On stimulation of the receptor, Adenyl cyclase is activated and cAMP is generated activating multiple downstream mediators involved in melanogenesis and melanocyte proliferation. Adapted from Joshi et al. (22) work with modification.