Table 5.
Biomarker area under the receiver operating characteristic curve values for the discrimination of septic peritonitis from non-septic ascites in dogs.
| Parameter | AUROC | 95% Confidence interval | P-value |
|---|---|---|---|
| CCL2 (Blood) | 0.778 | 0.625–0.931 | 0.0039 |
| Lactate (Effusion) | 0.866 | 0.751–0.980 | 0.0001 |
| CCL2 (Effusion) | 0.804 | 0.647–0.961 | 0.0016 |
| IL-6 (Effusion) | 0.803 | 0.662–0.943 | 0.0017 |
| IL-10 (Effusion) | 0.836 | 0.694–0.978 | 0.0005 |
| Lactate (Gradient) | 0.797 | 0.630–0.963 | 0.0020 |
| Glucose (Gradient) | 0.809 | 0.653–0.964 | 0.0013 |
| CCL2 (Gradient) | 0.817 | 0.667–0.968 | 0.0010 |
| IL-6 (Gradient) | 0.807 | 0.669–0.946 | 0.0014 |
| IL-10 (Gradient) | 0.817 | 0.662–0.973 | 0.0010 |
Area under the receiver operating characteristic curve values for the ability of measured biomarkers to discriminate dogs with SP and NSA. P-values represent the significance of the difference between the AUROC value and 0.5. AUROC, area under the receiver operating characteristic curve; CCL2, C-C Motif Chemokine Ligand-2; IL, interleukin.