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SFN administration suppressed the I/R-induced inflammatory cytokines production. (a and b) Relative mRNA expressions of TNF-α (a) and IL-1β (b) were analyzed in control group, I/R injury group, and I/R + SFN (5, 10, and 20 mg/kg) group using qRT-PCR. (c and d) The protein level of (c) TNF-α and (d) IL-1β in retinas was quantified by ELISA. Data are presented as mean ± SD, n = 6 for each group, *P < 0.05, **P < 0.01 compared to control group, tP < 0.05 compared to I/R group.
