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SFN administration suppresses the inflammasome activation. (a) Western blot analysis of inflammasome complex components (b) NLRP3, (c) ASC, and (d) Caspase-1 in control, I/R injury, and I/R + SFN (5, 10, and 20 mg/kg) treated rat retinas. qRT-PCR analysis of (e) NLRP3, (f) ASC, and (g) Caspase-1 in indicated treatment. Data are presented as mean ± SD, n = 6 for each group, *P < 0.05, **P < 0.01 compared to control group, tP < 0.05, ttP < 0.01 compared to I/R group.
