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. 2019 Jul 3;10:2040622319860653. doi: 10.1177/2040622319860653

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© The Author(s), 2019

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 7. — LGG reconstructed the intestinal microbial ecosystem at 8 weeks.

(a) A Venn diagram of shared and unique OTUs at 97% identity. (b) Beta diversity indices of the PCoA. PC1 and PC3 explained 35.77% and 8.77% of the variation observed, respectively (p = 0.001). (c) Histogram of the LDA scores showing significantly different microbiota compositions. The blue box represents highly abundant species in the LGG+TDF group. The yellow box represents highly abundant species in the TDF group.

LDA, linear discriminant analysis; LGG, Lactobacillus rhamnosus GG; OTUs, operational taxonomic units; PC1, ; PCoA, principal co-ordinates analysis; TDF, tenofovir disoproxil fumarate; ZOL, zoledronic acid.