Table 1.
The specific genetic risk factors that have so far been identified predisposing an individual to acquiring IgA vasculitis and those implicated in being protective against the disease [adapted from He et al. (12)].
| Genetic susceptibility | Genetic protection |
|---|---|
| HLA-B*15 | HLA-B*7 |
| HLA-B*35 | HLA-B*40 |
| HLA-B*4102 | HLA-B*49 |
| HLA-B*52 | HLA-B*50 |
| HLA-A*2 | HLA-A*1 |
| HLA-A*11 | HLADRB1*3 |
| HLA-A*26 | HLADRB1*7 |
| HLA-DRB1*0103 | Agtrs699M235T |
| HLA-DRB1*11 | MEFV |
| HLA-DQA1*0301 | PONI |
| HSPA21267GG | |
| IL1815187238-137G | |
| MCP1-2518TT | |
| MCP1-2518T | |
| TGF beta rs1800469-509TT | |
| Agt | |
| ACE | |
| C1GALT1rs | |
| NOS2A | |
| eNOS | |
| PONI192QQ | |
| MEFV |