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. Author manuscript; available in PMC: 2020 Jan 1.
Published in final edited form as: Mol Cancer Res. 2019 Apr 11;17(7):1582–1593. doi: 10.1158/1541-7786.MCR-18-1127

Fig. 4. Expression level validation of targeted DEGs and metabolite profiles of AA metabolism pathway.

Fig. 4.

(A) Relative mRNA expression level of Igf2, Src, Pak6 and Mmp7 were shown to be significantly up-regulated in tumors of HBx-B Mut/shp53 injected cohort compared with empty control. Mean ± S.D.; p, unpaired student t-test, *, p ≤ 0.05, **, p ≤ 0.01, ***, p ≤ 0.001. (B) Significantly higher ion abundance of prostaglandin B2, D2 and E2, leukotriene B4 and 12-HETE in HBx experimental cohorts compared to empty control. Mean ± S.D.; p, unpaired student t-test, *, p ≤ 0.05, **, p ≤ 0.01, ***, p ≤ 0.001.