Table 2.

Continuous Glucose Monitoring Systems Available in the Intensive Care Unit.

Device	Manufacturer	Sampling site	Technology	Interval	Comments	Studies	Regulatory status
GlucoScout	International Biomedical (Austin, TX, USA)	Venous or arterial	Electrochemical:Glucose oxidase	5 min	Calibration required	Glucose measurement accuracy Ganesh et al67	FDA 2013
OptiScanner 5000	Optiscan Biomedical (Hayward, CA, USA)	Connects to the proximal port of a central venous catheter	Infrared spectroscopy	15 min	No calibration required	Multiple studies Glucose measurement accuracy68-75	FDA 2017 and CE Mark 2011
Glucoclear™	Edward Life Sciences (Irvine, CA, USA)	Specialized peripheral venous catheter	Electrochemical:Glucose oxidase		No information available	Commercialization on hold	CE mark
Glysure	Glysure (Abingdon, UK)	Specialized multilumen central venous catheter	Fluorescence sensor	15 sec	No recalibration required	Glucose measurement accuracy Crane et al76	CE mark 2015 Submission to FDA pending
Eirus™	Maquet (Rastatt, Germany)	Specialized multilumen central venous catheter	Electrochemical:Glucose oxidase	Continuous	Highly accurate	Glucose measurement accuracy Schierenbeck72,77-79	CE marking Europe
OptiScanner	Optiscan Biomedical (Hayward, CA, USA)	Connects to the proximal port of a central venous catheter	Infrared spectroscopy	15 min	No calibration required	Multiple studies Glucose measurement accuracy68-75	FDA 2017 and CE Mark 2011
Sentrino®	Medtronic (Northridge, CA, USA)	Subcutaneous	Electrochemical:Glucose oxidase		Commercialization on hold	Glucose measurement accuracy80-83	CE Mark 2012