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. 2019 Jul 3;9:9607. doi: 10.1038/s41598-019-46119-6

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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LV hemodynamics and perfusion measurements. (A,B) LV end-systolic pressure (LVESP) and LV end-diastolic pressure (LVEDP) in Sham-operated (circle, n = 8), after ischemia-reperfusion (IR) (square, n = 8) and in MCP-treated IR rats (triangle, n = 7). (C,D) LV end-systolic pressure-volume relation (LVESPVR i.e. LV contractility) and LV end-diastolic pressure-volume relation (LVEDPVR i.e. LV compliance) in Sham-operated (circle, n = 8), after ischemia-reperfusion (IR) (square, n = 8) and in MCP-treated IR rats (triangle, n = 7). (E,F) Interventricular septum (Sept) and LV-free wall (LV-fw) myocardial perfusion in Sham-operated (circle, n = 10), after ischemia-reperfusion (IR) (square, n = 10) and in MCP-treated IR rats (triangle, n = 10). Histogram bars represent the mean ± SEM of each group. ***p < 0.001 vs. Sham-operated; ^†p < 0.05 and ^††p < 0.01 vs. IR.