Table 2.

Adverse outcomes or complications associated with methylnaltrexone use.

	Age	Gender	Cancer	Abdominal surgery	Radiation therapy	Adverse outcomes or complications	Timing after dose
1	58	F	pancreatic	yes	no	Free air (in the setting of worsening distention, clostridium difficile, and cecostomy)	9 days
2	84	F	pancreatic	no	no	Elevated lactic acid	1 day
3	57	F	pancreatic	yes	no	Perforation	1 day