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. 2019 Jul 3;9:9596. doi: 10.1038/s41598-019-46116-9

Figure 7.

Figure 7

Neutrophil accumulation after LPS application is diminished in NLRP3 KO mice. Gr-1-positive cells (arrows), which account for neutrophil, are infiltrated in anterior stroma of WT mice 2 days after LPS application. (a) In NLRP3 KO mice (b), this accumulation is canceled, and the Gr-1-positive cells are significantly fewer compared with those of WT mice (N = 3 each, WT mice; 12.3 ± 1.5 cells/field, NLRP3 KO mice; 1.2 ± 1.1 cells/field, P < 0.01, ManneWhitney U-test) (c). Bar = 40 μm.