Figure 4.

Stability of miR-155-5p-Loaded NPs after Preparation (Day 0) and after 1, 7, 14, 21, and 28 Days of Storage at 4°C

NP diameter (nm) (A) and PdI (B) were measured by DLS and ζ potential values (mV) by ELS (C). miRNA presence (% in relation to the control at day 0) within loaded NPs was observed through AGE (D). Outputs from unloaded NPs are also represented (white symbols). Results are shown as the mean ± SD from three to four independent experiments. Significant differences were detected for loaded NPs using the Wilcoxon matched-pairs signed rank test; *p < 0.05.