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. 2019 Jun 12;17:223–234. doi: 10.1016/j.omtn.2019.06.001

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© 2019 The Author(s)

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Overexpression of miRNA-26a-5p in TBI Patients

(A) The fracture+TBI group showed a faster fracture healing rate than the isolated-fracture group. (a) preoperative three-dimensional CT image; anteroposterior (b) and lateral (c) radiographic images at 1 month after surgery; anteroposterior (d) and lateral (e) radiographic images 3 months after surgery; and anteroposterior (f) and lateral (g) radiographic images 1-year after surgery. (B) Relative expression of miRNA-26a-5p was higher in serum samples of the fracture+TBI group than the other groups. (C) The calluses at the fracture site were more visible in fracture+TBI group when compared with those in the fracture group. (D) The fracture+TBI group showed a higher level of miRNA-26a-5p than the other groups. Data are means ± SD. *p < 0.05, **p < 0.01, ***p < 0.001. n = 6 patients in each group.