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. 2019 Jun 12;17:223–234. doi: 10.1016/j.omtn.2019.06.001

Figure 7.

Figure 7

A Diagrammatic Sketch of miR-26a-5p-Mediated Osteoblast Differentiation

miR-26a-5p is upregulated in bone and reduces PTEN translation, thereby activating the PI3K-AKT signaling pathway, subsequently inducing RunX2 expression and increasing bone formation.