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. Author manuscript; available in PMC: 2020 Aug 1.
Published in final edited form as: Drug Deliv Transl Res. 2019 Aug;9(4):802–815. doi: 10.1007/s13346-019-00630-5

Fig 2.

Fig 2

In vitro release of tobramycin (TOB) and vancomycin (VANC) from PNDJ hydrogels is affected by JAAm content but not by drug loading ratio. (a) Antimicrobial release from PNDJ hydrogels with varying JAAm content loaded with 9 drug loading combinations (2.35–3.14% tobramycin, 0.78–2.35% vancomycin; see Online Resource Fig 1a). (b) Percentage of antimicrobials released from PNDJ hydrogels with varying JAAm content (1.02–1.45 mol%) and drug loading (2.35–3.14% tobramycin, 0.78–2.35% vancomycin) at 70 hr. Each box-and-whisker plot represents the distribution of data from 9 drug loading combinations within the gel (described further in Online Resource Fig 1a). Significant differences in antimicrobial release (adjusted p < 0.01) were identified for gels in comparison to PNDJ1.02 (*) and PNDJ1.45 (#) using a oneway ANOVA with Bonferroni post-test for multiple comparisons