Table 5:

Models for Predicting 30-day mortality

Model incorporating Nosocomial infections as Yes/No					Model incorporating Infections as ordinal variables
Variable	p-value	OR (95% CI)	AUC (95%CI)	Sensitivity/ Specificity	Variable	p-value	OR (95% CI)	AUC (95%CI)	Sensitivity/ Specificity
Age	<0.0001	1.04 (1.03, 1.06)	0.84 (0.82, 0.89)	0.83 /0.72	Age	<0.0001	1.05 (1.03, 1.06)	0.84 (0.81, 0.87)	0.73/ 0.83
Rifaximin at Admission	0.0282	0.68 (0.48, 0.96)			Alcoholic Etiology	0.0240	1.45 (1.05, 2.00)
Lactulose at Admission	0.0445	1.42 (1.01, 2.0)			PPI at Admission	0.0133	0.67 (0.49, 0.92)
Episodes of AKI	<0.0001	2.17 (1.51, 3.14)			Rifaximin at Admission	0.0064	0.61 (0.42, 0.87)
MELD	<0.0001	1.07 (1.05, 1.09)			Lactulose at Admission	0.0203	1.52 (1.07, 2.17)
ICU Admission	0.0003	1.99 (1.38, 2.87)			Episodes of AKI	<0.0001	2.27 (1.56, 3.30)
ACLF	<0.0001	3.34 (2.23, 5.01)			MELD	<0.0001	1.31 (1.04, 1.08)
Nosocomial Infection	0.0002	1.96 (1.37, 2.80)			ICU Admission	0.0012	1.89 (1.29, 2.77)
					ACLF	<0.0001	3.57 (2.34, 5.44)
					Infection Variable 0 1 2 3	0.0047	--- 1 vs 0 1.14 (0.75, 1.73) 2 vs 0 2.22 (1.42,3.50) 3 vs 0 1.56 (1.01, 2.56)

Ordinal variable; 0=no infections, 1=admission infection only, 2=no admission infection but nosocomial infection, 3=both admission and nosocomial infections

For Yes/No model n = 2,198. For ordinal infection model, n = 2,149