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Increased activation of STAT3 signaling in the inflamed ileum of Crohn's disease patients. (a) Representative images of pSTAT3-Y705 IHC staining on unaffected (n = 6) and inflamed ileum of CD patients (n = 10). pSTAT3+ cells were shown as brown dots. Images were obtained under 20x magnification. Scale bar = 50 μm. (b) Statistical analysis of pSTAT3-Y705+ cells per HPF in unaffected and inflamed ileum of CD patients. Unpaired Mann-Whitney t test was performed, α = 0.05.
