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. 2019 Jul 3;17:115. doi: 10.1186/s12957-019-1659-8

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Patterns of CD21 and CD23 expression by the follicular dendritic cells. Pattern 1 describes diffuse staining of FDCs in the germinal center while pattern 2 demonstrates the peripheral staining in a “crescetic” fashion. Pattern 3 shows broken networks of the FDCs while the follicular outline is preserved. In pattern 4, the follicular outline is lost. Pattern 5 shows lack of stain and, in pattern 6, there is staining of FDC extensions around the individual mantle zone B cells