Table 3.
No. | 5-year OS | 5-year DFS | 5-year LRFS | 5-year DMFS | |||||
---|---|---|---|---|---|---|---|---|---|
% | P value | % | P value | % | P value | % | P value | ||
Age (years) | |||||||||
≤ 60 | 74 | 85.9 | < 0.001 | 77.4 | 0.001 | 89.4 | 0.236 | 84.4 | 0.002 |
> 60 | 25 | 52.0 | 43.2 | 83.6 | 55.7 | ||||
Tumor size (cm) | |||||||||
≤ 5 | 34 | 87.5 | 0.130 | 78.0 | 0.229 | 96.7 | 0.162 | 84.2 | 0.263 |
> 5 | 61 | 69.8 | 63.5 | 82.3 | 71.8 | ||||
Tumor depth | |||||||||
Superficial | 30 | 89.3 | 0.205 | 79.0 | 0.300 | 92.6 | 0.734 | 86.2 | 0.296 |
Deep | 69 | 71.9 | 65.8 | 86.2 | 73.2 | ||||
FNCLCC grade | |||||||||
1–2 | 67 | 84.8 | 0.012 | 81.5 | < 0.001 | 93.4 | 0.008 | 84.5 | 0.003 |
3 | 32 | 60.2 | 44.8 | 75.3 | 61.4 | ||||
Resection margin | |||||||||
Negative | 77 | 80.0 | 0.065 | 73.6 | 0.109 | 93.9 | 0.001 | 78.9 | 0.202 |
Close or Positive | 19 | 67.4 | 52.6 | 65.1 | 68.0 | ||||
Chemotherapy | |||||||||
No | 58 | 80.2 | 0.522 | 73.0 | 0.535 | 86.0 | 0.313 | 84.0 | 0.115 |
Yes | 41 | 72.7 | 65.5 | 91.5 | 67.9 | ||||
Hemoglobin (g/dL) | |||||||||
≥ 12 | 84 | 76.7 | 0.914 | 68.0 | 0.398 | 87.5 | 0.574 | 76.6 | 0.765 |
< 12 | 15 | 79.4 | 80.0 | 93.3 | 80.0 | ||||
CRP (mg/dL) | |||||||||
≤ 0.14 | 61 | 84.5 | 0.050 | 79.3 | 0.023 | 92.6 | 0.376 | 84.5 | 0.015 |
> 0.14 | 33 | 69.3 | 57.1 | 84.1 | 66.5 | ||||
ESR (mm/h) | |||||||||
≤ 15 | 47 | 91.2 | 0.001 | 89.1 | 0.003 | 97.7 | 0.035 | 93.5 | 0.001 |
> 15 | 44 | 69.4 | 57.8 | 80.6 | 67.4 | ||||
NLR | |||||||||
≤ 1.95 | 52 | 84.0 | 0.054 | 78.4 | 0.174 | 89.3 | 0.793 | 84.4 | 0.170 |
> 1.95 | 45 | 70.2 | 63.0 | 89.0 | 69.9 |
Abbreviations: OS overall survival, DFS disease-free survival, DMFS distant metastasis-free survival, LRFS local recurrence-free survival, FNCLCC Fédération Nationale des Centres de Lutte Contre le Cancer, CRP C-reactive protein, ESR erythrocyte sedimentation rate, NLR neutrophil to lymphocyte ratio