Fig. 4.

Functional analysis of mmu-mir-146a, mmu-mir-182, and mmu-mir-200b. a–c The protein-protein interaction for the predicted genes of each miRNA and the principal KEGG pathways modulated by the STRING protein proteins network interaction analysis performed with the STRING webserver. The p values are represented as (-log(p value)). d Heatmap of the modified principal KEGG pathways derived from the genes simultaneously affected by mir-146a and mir-182. e The protein-protein interaction for the predicted genes simultaneously modulated by mir-146a and mir-182 by the STRING webserver database. Arrows indicate the genes selected for the gene expression analysis shown in Fig. 7b