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. 2019 Jun 28;9:563. doi: 10.3389/fonc.2019.00563

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Copyright © 2019 Larousserie, Kebe, Huynh, Audebourg, Tamburini, Terris and Devergne.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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IL-35 is overexpressed in DLBCL compared to BL. (A–C) Gene expression values for EBI3 and p35 (IL12A) from B-cell lymphomas classified by molecular profiling as Burkitt lymphoma (mBL) or DLBCL (mDLBCL) were extracted from GSE4475 (A) and GSE4732 (B). While the microaarrays used in these studies do not contain probes for p28 gene, a subgroup of samples from the GSE4732 study was analyzed using U133 Plus 2.0 array that contains a probe for p28, and gene expression of EBI3, p35 and p28 (IL27) for this subset of samples is shown in (C). Data (normalized signal intensity) are represented as box plot (10–90% percentile) and outliers are shown. p-values of t-tests are indicated.